Not at all. You will need to get it tuned, though. I used the injectors that came with the newer engine. They're 19 or 21 lbs as opposed to the 14lbs you have now. To do this, however .. You either need to buy pigtail adapter or splice in the pigtails from the newer harness because the connector is different on the injectors. Other than the few things you need to swap over, everything is a piece of cake.
You can part out a lot of that 2000 if you don't need it. Just a heads up, if you like anything in the interior, the interiors are pretty much interchangeable between years. Make a list of everything you don't need and hit up our For Sale forum to make some of your money back. Anything too big to ship, put on Craigslist. You'll come off pretty decent. Especially with a New Edge. Everybody's always looking for spare parts.
1996 3.8L.. Split Port Swap, CAI, True Dual Exhaust, the car accident mod.
Need cheap parts? CLICK MEEEEEEEEE!! =]